SUPER ANTI-AGEING OXYGEN FACE CREAM - Anti-Ageing Cellular Renewal Cream

$119 $149

The Anti-Ageing Cellular Renewal Cream by L’Ossigeno is an all-in-one cream that nourishes and regularises the skin's physiological function and is the ideal product to reduce the effects of time on the skin.

Penetrating in the deep layers, its formulation rich in Oxygen Ozone reactivates the vitality of the cells, stimulating the production of new collagen and elastic fibers. The presence of Collagen and Hyaluronic Acid guarantees lasting hydration to make the skin firm, while visibly reducing fine lines and wrinkles.

The active ingredients and vitamins within its formulation provide the skin with nourishment and moisturisation to reduce oxidative stress caused by external agents - the physiological ageing process is therefore visibly mitigated.


Anti-Ageing Cellular Renewal Cream

✓ Specifically Targets Fine Lines & Wrinkles
✓ Anti-Ageing Ingredient Rich
✓ Stimulates Collagen & New Elastic Fibres
✓ Encourages Regular Cellular Renewal
✓ Fast Absorption & Fast Acting
✓ Strong Antioxidant Properties

Benefits of Oxygen Ozone
Oxygen Ozone repairs the skin cells from damage caused by free radicals and oxidative stress. The result is a hydrated and active cell, which leads to younger and firmer skin within weeks.

✓ Enhancement of Tissue Oxygenation
✓ Improved Skin Firmness & Elasticity
✓ Oxidative Stress Protection
✓ Cellular Vitality Improvement
✓ Skin Rejuvenation


Key Active Ingredients
Oxygen Ozone | Vitamin E | Vitamin A | Collagen | Lactic Acid | Hyaluronic Acid | Argan Oil

Ingredient Listing
Aqua | Ethylhexyl Palmitate | Ozonized Glycerin | Cetearyl Isononanoate | Tocopheryl Acetate | Ceteareth-20 | Cetearyl Alcohol | Argania Spinosa Kernel Oil | Phenoxyethanol | Carbomer | Hydrolyzed Collagen | Retinyl Palmitate | Glycerin | Glyceryl Stearate | Imidazolidinyl Urea | Helianthus Annuus Seed Oil | Triethanolamine | Potassium Sorbate | Lecithin | Pentylene Glycol |Benzoic Acid | Ceteareth-12 | Cetyl Palmitate | Lactic Acid | Hyaluronic Acid | Tocopherold


Splash face with warm water and wash with a cleanser, preferably the Deep Regenerating Cleanser (no need to tone when using this). The activated Oxygen Ozone & Hyaluronic Acid will cleanse and make the skin highly receptive to further treatment.

Apply a small amount of the Hyaluronic Serum Concentrate onto the fingertips and massage gently onto the face with circular movements until completely absorbed. Focus on areas under the eyes, in the T section, and areas of dryness. For best results, apply in the morning and in the evening.

Apply a small amount of your preferred L'Ossigeno Gel Treatment and massage gently all over the face. This will provide instant hydration, oxygenation, and give firmness to the skin.

Dispense a small amount of Anti-Ageing Cellular Renewal Cream onto the fingertips and massage gently onto the face with circular movements until completely absorbed. For best results, apply in the morning and in the evening after facial cleansing. For external use only. In case of pregnancy, consult a doctor before use.


The Exclusive Unique Combination


As time goes by due to normal aging, the metabolism of the skin cell slows down as they decrease their ability to transform oxygen and retain water. The decrease in efficiency of cellular renewal represents one of the most important aging signs.

The unique combination of Oxygen Ozone, the core active ingredient in the entire L'Ossigeno range, offers a re-oxygenating effect on the skin cells to favour skin cell renewal, resulting in a more elastic and younger final appearance of the skin. The cellular metabolic reactivation enhances the production of new collagen and new elastic fibres, restoring the skins natural radiance.

The chemical structure of the Oxygen Ozone combination allows a rapid absorption through the skin layers, engendering an immediate and effective result. The combination has been scientifically tested and proven to increase cell vitality at both the University of Pisa and the University of Genova.

The unique combination of Oxygen Ozone is a patented process created by Dr. Roberto Albertelli.


The Anti-Ageing Cellular Renewal Cream is an all-in-one cream that has all of the best ingredients to provide the skin with strong anti-ageing benefits. It has a rapid absorption and works very efficiently at oxygenating and nourishing the skin. If you are looking for a simple, yet effective routine, this is the only cream you need.



University of Genoa

Genova, Italy

The L'Ossigeno Gel Treatments are able to protect the epidermis from factors that cause oxidative stress such as ageing and pollution.
University of Pisa

Department of Microbiology
The Oxygen Ozone present in the L'Ossigeno Skincare Collection increase cellular activity in skin cells by 300%.

BIOXID-AD Laboratory

Tuscany, Italy

L'Ossigeno products work effectively on skin restoring the cellular metabolic balance. Consequently, the cell is able not only to physiologically react to endogenous and exogenous damages but also to absorb in a faster way the active ingredients present in the product.


BioBasic Laboratory

Milan, Italy

Oxygen Ozone is capable of reducing interleukin production in human keratinocyte cells in vitro.

BioBasic Laboratory

Milan, Italy

The anti-ageing L'Ossigeno collection offers a repairing action against environmental stress (pollution and UV radiation) tested on the in vitro keratinocytes cells.


The Anti-Ageing Cellular Renewal Cream is an all-in-one product that can be used alone after cleansing. If you are looking to extend your routine further, it works very well with our Hyaluronic Serum Concentrate and any L'Ossigeno Gel Treatment.

Ships from Adelaide, Australia

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Can I use this if I'm pregnant or breastfeeding?
Yes, oxygen ozone is completely safe. All products in our collection that do not contain Vitamin A are safe to use while pregnant or breastfeeding. Products that contain Vitamin A are recommended to speak with a doctor before using. 

What if I do not like the products?
If you are not 100% satisfied with your L'Ossigeno skincare at any stage within 30 days, email us and you will receive a 100% refund, even if the products are used.

Where are the products made?
The L'Ossigeno collection is made in Forte Dei Marmi, in Tuscany, Italy. Our main office is in Adelaide, Australia where products are dispatched from.

How long is shipping?
Complimentary express shipping within Australia: 1-2 Business Days.
DHL Express worldwide: 4-5 Business Days. 

How long will one product last me?
On average, our 50ml products last for about 2 months of daily use. 

What is Oxygen Ozone and how does it help the skin?
Oxygen Ozone the core ingredient in the entire L'Ossigeno collection, which is an ionised Oxygen gel that directly and instantly provides the skin cells with oxygen ions. By providing oxygen directly to the skin cells, the cell is nourished, the vitality of the cell increases, and the skin is protected from oxidative stress and free radicals. This process gives the skin a younger & firmer appearance. Oxygen Ozone also makes the skin more receptive to the additional active ingredients present in the products.

Are there preservatives in L'Ossigeno?
L'Ossigeno has less preservatives than most other skincare products on the market due to the natural anti-bacterial nature of Oxygen Ozone. L'Ossigeno has no parabens and uses no fragrances.

Are L'Ossigeno products Vegan?
Yes, all products in the L'Ossigeno collection that do not have collagen as an ingredient are vegan. 

What does L'Ossigeno mean?
L'Ossigeno is Italian for "the Oxygen" as our entire collection is made using our patented core ingredient Oxygen Ozone.

Customer Reviews

Based on 6 reviews
Ali Gelekis
Silky hydration

This is a beautiful, lightweight and silky cream that is hydrating without being heavy or greasy. Leaves the skin looking fresh and glowy on its own and sits well under makeup too. Packaging looks so luxe sitting on my vanity!

My best anti-stress skin routine

Every day I can’t wait to come back to work, remove my make up and massage my skin with a small amount of this product!

Amazing traitment for me, like beauty lab! Hydrate and Nourish Skin sensation, visible reduce oxidative stress caused by external agents: perfect also after strong Australian sunbath!

I'm curious to see further improvements!
Thank you L’Ossigeno

Kurt Corsini
Amazing stuff, 6 weeks and my skin looks unreal

I have been using L’Ossigeno for almost 6 weeks and can already start to see and feel results. Smoothness and texture of my skin has improved which generally looks much healthier. My skin is on the sensitive side; however, I have had no irritation issues at all using this cream. Definitely recommend adding this to your daily routine. Thank you L’Ossigeno!

Belinda Callisto
I swear it has made my lines smoother!

I’ve been using L’Ossigeno for 2 weeks and I’m loving this cream. I swear it has made my lines smoother and my overall face feels more hydrated and fresh. Thank you L’Ossigeno

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L'Ossigeno Skincare

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