WATER-BASED OXYGEN CLEANSER with HA - Regenerating Deep Cleanser


The Regenerating Deep Cleanser by L’Ossigeno is the ideal cleansing solution for all skin types: it gently cleanses the skin deeply by removing impurities such as air pollution, sebum, and make-up residues and restores the skin's vitality and natural freshness. Its purifying and effective action is gentle and does not alter the skin's natural defences, allowing the Hyaluronic Acid to deeply moisturise while the combination of Oxygen Ozone protects and repairs the skin from damage caused by make-up and smog. The skin is brighter, cleaner, and more receptive to subsequent treatments.  

No face toner is required after the Regenerating Deep Cleanser


Regenerating Deep Cleanser

✓ Provides a Deep, yet Gentle Cleanse
✓ Enriched with Hyaluronic Acid
✓ Suitable for All Skin Types
✓ Removes Fine Dust, Air Pollution, Dead Skin, Water-Resistant Make-Up & other Impurities from Pores
✓ Improves Microcirculation & Promotes Natural Cellular Turnover
✓ Skin is Revitalised, Moisturised, Smooth & Receptive to Further Treatment

Benefits of Oxygen Ozone
Oxygen Ozone repairs the skin cells from damage caused by free radicals and oxidative stress. The result is a hydrated and active cell, which leads to younger and firmer skin within weeks.

✓ Enhancement of Tissue Oxygenation
✓ Improved Skin Firmness & Elasticity
✓ Oxidative Stress Protection
✓ Cellular Vitality Improvement
✓ Skin Rejuvenation


Key Active Ingredients
Oxygen Ozone | Hyaluronic Acid

Ingredient Listing
Aqua | Cetearyl Alcohol | Ethylhexyl Palmitate | Propylene Glycol | Polysorbate 60 | Ozonized Glycerin | Phenethyl Alcohol | Phenoxyethanol | Glycerin | Lecithin | Pentylene Glycol | Caprylhydroxamic Acid | PEG-150 Stearate | Steareth-20 | Lactic Acid | Hyaluronic Acid


Pour a small amount of the Regenerating Deep Cleanser onto a cotton pad and pass with circular movements all over the face, neck, and décolleté until completely cleansed. Rinse with warm water afterwards. Apply in the morning and in the evening before any treatment. For external use only. The activated Oxygen Ozone & Hyaluronic Acid will cleanse and make the skin highly receptive to further treatment.

Apply a small amount of the Hyaluronic Serum Concentrate onto the fingertips and massage gently onto the face with circular movements until completely absorbed. Focus on areas under the eyes, in the T section, and areas of dryness. For best results, apply in the morning and in the evening.

Apply a small amount of your preferred L'Ossigeno Gel Treatment and massage gently all over the face. This will provide instant hydration, oxygenation, and give firmness to the skin.

If needed for dryer skin, apply the Overnight Cellular Recovery Cream for extra hydration and anti-ageing benefits.


The Exclusive Unique Combination


As time goes by due to normal aging, the metabolism of the skin cell slows down as they decrease their ability to transform oxygen and retain water. The decrease in efficiency of cellular renewal represents one of the most important aging signs.

The unique combination of Oxygen Ozone, the core active ingredient in the entire L'Ossigeno range, offers a re-oxygenating effect on the skin cells to favour skin cell renewal, resulting in a more elastic and younger final appearance of the skin. The cellular metabolic reactivation enhances the production of new collagen and new elastic fibres, restoring the skins natural radiance.

The chemical structure of the Oxygen Ozone combination allows a rapid absorption through the skin layers, engendering an immediate and effective result. The combination has been scientifically tested and proven to increase cell vitality at both the University of Pisa and the University of Genova.

The unique combination of Oxygen Ozone is a patented process created by Dr. Roberto Albertelli.


The Deep Regenerating Cleanser is a fantastic water-based cleanser that hydrates and soothes the skin while removing any dirt or make-up. The Oxygen Ozone provides the skin with the benefits of Oxygen while cleaning, nourishing, and making the skin ready for treatment.



University of Genoa

Genova, Italy

The L'Ossigeno Gel Treatments are able to protect the epidermis from factors that cause oxidative stress such as ageing and pollution.
University of Pisa

Department of Microbiology
The Oxygen Ozone present in the L'Ossigeno Skincare Collection increase cellular activity in skin cells by 300%.

BIOXID-AD Laboratory

Tuscany, Italy

L'Ossigeno products work effectively on skin restoring the cellular metabolic balance. Consequently, the cell is able not only to physiologically react to endogenous and exogenous damages but also to absorb in a faster way the active ingredients present in the product.


BioBasic Laboratory

Milan, Italy

Oxygen Ozone is capable of reducing interleukin production in human keratinocyte cells in vitro.

BioBasic Laboratory

Milan, Italy

The anti-ageing L'Ossigeno collection offers a repairing action against environmental stress (pollution and UV radiation) tested on the in vitro keratinocytes cells.


The Deep Regenerating Cleanser is a staple product suitable for all skin types that should be used in all skincare routines.

Ships from Adelaide, Australia

Free Shipping & Returns

This item is in stock
24 Hour Dispatch

Can I use this if I'm pregnant or breastfeeding?
Yes, oxygen ozone is completely safe. All products in our collection that do not contain Vitamin A are safe to use while pregnant or breastfeeding. Products that contain Vitamin A are recommended to speak with a doctor before using. 

What if I do not like the products?
If you are not 100% satisfied with your L'Ossigeno skincare at any stage within 30 days, email us and you will receive a 100% refund, even if the products are used.

Where are the products made?
The L'Ossigeno collection is made in Forte Dei Marmi, in Tuscany, Italy. Our main office is in Adelaide, Australia where products are dispatched from.

How long is shipping?
Complimentary express shipping within Australia: 1-2 Business Days.
DHL Express worldwide: 4-5 Business Days. 

How long will one product last me?
On average, our 50ml products last for about 2 months of daily use. 

What is Oxygen Ozone and how does it help the skin?
Oxygen Ozone the core ingredient in the entire L'Ossigeno collection, which is an ionised Oxygen gel that directly and instantly provides the skin cells with oxygen ions. By providing oxygen directly to the skin cells, the cell is nourished, the vitality of the cell increases, and the skin is protected from oxidative stress and free radicals. This process gives the skin a younger & firmer appearance. Oxygen Ozone also makes the skin more receptive to the additional active ingredients present in the products.

Are there preservatives in L'Ossigeno?
L'Ossigeno has less preservatives than most other skincare products on the market due to the natural anti-bacterial nature of Oxygen Ozone. L'Ossigeno has no parabens and uses no fragrances.

Are L'Ossigeno products Vegan?
Yes, all products in the L'Ossigeno collection that do not have collagen as an ingredient are vegan. 

What does L'Ossigeno mean?
L'Ossigeno is Italian for "the Oxygen" as our entire collection is made using our patented core ingredient Oxygen Ozone.

Customer Reviews

Based on 2 reviews
Ali Gelekis
New morning fave

I have to wear full makeup for work so I generally haven't liked cream cleansers in the past because they don't remove all my makeup. I double cleanse at night to get rid of it all, so I don't normally cleanse in the morning, but now I do with this product! It's perfect for my morning cleanse and leaves my skin feeling fresh and really soft, so happy with this new addition to my routine! Love the luxurious frosted glass bottle too

Soothing and Creamy

This has to be one of the best cleansers I have ever used. Immediately afterwards my skin feels so clean and refreshed. It is creamy and works well on both dry and wet skin, so glad I have finally found a decent cleanser that removes my make-up in one hit!

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L'Ossigeno Skincare

◾️ Patented & Exclusive Oxygen Ozone Formula
◾️ Australian Owned & Operated
◾️ Clinically & University Proven
◾️ Fast Results Guaranteed